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PHYTOCANNABINOIDS

Natures very own cure 

Cannabis contains at least 489 chemical constituents, of which more than 100 are Phytocannabinoids. THC and CBD are the main constituents of cannabis. THC activates both CB1 and CB2 receptors while CBD does not directly bind to these receptors but it has the ability to get the body to release endocannabinoid such as Anandamide and 2-arachidonoylglycerol or 2-AG

The Effects of Photocannabinoids

The effects of cannabinoids on emotional, cognitive and psychomotor function vary according to the experience of users and their condition at the time of consuming the drug. The most marked psychological effects of THC can be divided into four groups: 

  1. Affective (euphoria, cheerfulness),
  2. Sensoric (increased perception of external stimuli and one’s own body),
  3. Somatic (feeling of the body floating or falling),
  4. Cognitive (disturbed time perception, memory failure, troubles with concentration).

Cannabis also has many physical effects. These include the lowering of body temperature, reddened conjunctivae, reduced tear flow, decreased intraocular pressure, tachycardia, increased oxygen demands, vasodilatation, orthostatic or postural hypotension, hypertension, bronchodilation, hyposalivation, reduced bowel movement and delayed gastric emptying, as well as changes in the hormonal and immune systems.

Phytocannabinoids are plant-based equivalents to Endocannabinoids such as Anandamide and 2‑arachidonoylglycerol.

Multiple physical, psychological, and emotional benefits have been attributed to Cannabis since its first reported use in 2 600 BC (Source: www.ncbi.nlm.nih.gov/pubmed/29770251). The PhytoCannabinoids, Cannabidiol (CBD), and Delta-9-Tetrahydrocannabinol (Δ9-THC) are the most studied PhytoCannabinoids of the Cannabis Sativa plant. CBD and Δ9-THC interact uniquely with the Endocannabinoid System (ECS). Through direct and indirect actions, Endocannabinoids and plant-based Phytocannabinoids modulate and influence a variety of physiological systems.

In 1980, Cunha et al.  reported on the anticonvulsant benefits of Cannabis of eight subjects with medically uncontrolled epilepsy in a phase 1 clinical trial. Since then, neurological applications have been the major focus of renewed research using PhytoCannabinoids oil extracts. https://www.researchgate.net/publication/324777752_Review_of_the_neurological_benefits_of_phytocannabinoids 

Recent neurological uses include adjunctive treatment for malignant brain tumours, Parkinson's disease, Alzheimer's disease, multiple sclerosis, neuropathic pain and the childhood seizure disorders of Lennox-Gastaut and Dravet syndromes. In addition, psychiatric and mood disorders such as schizophrenia, anxiety, depression, addiction, post-concussion syndrome and posttraumatic stress disorders (PTSD) are being treated with PhytoCannabinoids.

Phytocannabinoid Profiles

Tetrahydrocannabinolic Acid (THC-A) Like other acid cannabinoids, it is not psychoactive. Further, THC-A is anti-inflammatory, anti-tumour, encourages appetite, combats insomnia and is antispasmodic.

CBD-A) is both anti-inflammatory and anti-tumour

One of the three compounds synthesized by the Cannabis plant, CBC-A is anti-inflammatory, weakly anti-fungal and strongly anti-bacterial.

Cannabigerolic acid is considered to be the ‘mother’ of all Cannabinoids. Transformed by the mother plant into all the other cannabinoids, it is the direct parent compound of CBG, a rare neuro-regenerative medicinal compound.

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The discovery of THC led scientists to discover the Endocannabinoid System in humans and other vertebrate animals, a critical aspect of physiology that, up until then, was unknown. THC is effective in the treatment of a variety of ailments and disorders including pain, tumours, nausea and ADHD /ADD

Some other benefits of THC include:
1) Excellent sleep aid
2) Pain Relief
3) Eases Nausea and vomiting
4) Increases Appetite
5) Enhances senses
6) Anti-Inflammatory
7) Antioxidant
8) Bronchodilator
9) Anti-tumor agent
10) Muscle relaxant
11) Anticonvulsant 

Is “non-psychoactive” in that it does not produce the euphoria, time dilation or anxiety characterised by THC. CBD as well as some other phytocannabinoids has the ability to dampen the effects of THC. In the full extract, CBD has been valuable in the treatment of seizure disorders such as MS (multiple sclerosis) and epilepsy, and it is often as effective as THC in the management of pain and tumours. CBD also lowers blood sugar, is used to treat Diabetes, and because of its calming effect, is useful for treating stress-related disorders and insomnia.
Some other benefits of CBD are:
1) Alleviate Cancer-Related Symptoms
2) Neuroprotective Properties
3) Heart Health
4) Relieve Pain
5) Reduce Anxiety and Depression 

Cannabichromene is non-psychoactive and about 10 times more effective than CBD in treating anxiety and stress. It also displays efficiency in treating inflammation and alleviating pain, stimulating the growth of bone tissue, and it is both anti-viral and anti-tumour.
Some other benefits of CBC are:
1) Antimicrobial / Anti-Viral
2) Anti-inflammatory
3) Analgesic
4) Anti-Depressant
5) Migraines 

Cannabigerol displays neuroprotective effects with Huntington’s, therapeutically as an antidepressant and as a painkiller. CBG’s antibacterial effects can alter the overall effects of cannabis. CBG is known to kill or slow bacterial growth, reduce inflammation, inhibit cell growth in tumour/cancer cells, and promote bone growth..
Some other benefits of CBG are:
1) Anti fungal effects
2) Useful in treatment of psoriasis
3) Helps fight breast cancer
4) Good for skin conditions  

This is an oxidation product of THC, normally formed when THC is exposed to oxygen and heat. CBN is the most sedative of all the Cannabinoids so it’s useful in the treatment of sleep disorders. It is also somewhat effective as an anti-emetic and anticonvulsant.
Some other benefits of CBN
1) Relieves pain
2) Aids with sleep
3) Promotes bone growth
4) Reduces inflammation
5) Inhibits cancer cell growth 

THCV doesn’t begin as cannabigerolic acid (CBGa). THCV is created from the break down of cannabigerovarin acid (CBGVA). Tetrahydrocannabivarin (THCV) is actually an antagonist (a type of receptor that blocks or dampens agonist-mediated responses rather than provoking a biological response itself upon binding to a receptor) of the CB1 and CB2 receptors.
Some other benefits of THCV are:
1) Appetite suppressant
2) Regulate blood sugar levels
3) Reduces panic attacks
4) Stimulates bone growth
5) Anti-convulsive 

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THIS MEDICINE HAS NOT BEEN EVALUATED BY THE MCC.
THIS MEDICINE IS NOT INTENDED TO DIAGNOSE OR PREVENT ANY DISEASE